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9 LEADING PUBLICATION REVIEWS
David Salas, PT, DPT, CSCS from Doctors of Running highlights the Brooks Glycerin 22 as a well-balanced, premium daily training shoe that delivers a plush yet responsive ride thanks to its innovative DNA Tuned midsole. This nitrogen-infused foam uses different cell sizes to provide a softer heel cushioning and a snappier forefoot push-off, making it a notable improvement over previous models. The shoe fits true to size with a secure lockdown and a roomy forefoot, though the heel counter is quite stiff and may not suit everyone. Stability is solid for a neutral trainer, aided by a wide base and good outsole traction, though the softer foam slightly reduces rearfoot stability. Salas appreciates the shoe’s traditional high-drop geometry and moderate flexibility, recommending it for runners seeking a comfortable, reliable daily trainer with a smooth ride. Minor critiques include a desire for a more rounded heel bevel to ease initial contact and a slightly plusher heel counter for added comfort.
David Marquez, David Kroeker-Maus, and Yannick Khong from RTINGS assess the Brooks Glycerin 22 as a premium daily trainer that excels in delivering smooth, plush comfort, particularly for heel strikers, thanks to its updated midsole and well-cushioned heel. The shoe’s “DNA Tuned” dual-density cushioning offers solid impact absorption and excellent lateral stability, making it a reliable, stable choice for everyday use and walking. However, the review highlights notable drawbacks: the shoe’s heavy weight and limited energy return result in a sluggish feel and reduced efficiency, especially for racing or long-distance runs. The forefoot cushioning is less protective and tends to bottom out over extended mileage, diminishing comfort during longer efforts. While the Glycerin 22 stands out for its comfort and stability, it falls short in responsiveness and speed, making it better suited for casual training rather than competitive racing or fast-paced workouts.
David Salas, PT, DPT, CSCS from Doctors of Running highlights the Brooks Glycerin 22 as a well-balanced, premium daily training shoe that delivers a plush yet responsive ride thanks to its innovative DNA Tuned midsole. This nitrogen-infused foam uses different cell sizes to provide a softer heel cushioning and a snappier forefoot push-off, making it a notable improvement over previous models. The shoe fits true to size with a secure lockdown and a roomy forefoot, though the heel counter is quite stiff and may not suit everyone. Stability is solid for a neutral trainer, aided by a wide base and good outsole traction, though the softer foam slightly reduces rearfoot stability. Salas appreciates the shoe’s traditional high-drop geometry and moderate flexibility, recommending it for runners seeking a comfortable, reliable daily trainer with a smooth ride. Minor critiques include a desire for a more rounded heel bevel to ease initial contact and a slightly plusher heel counter for added comfort.
David Marquez, David Kroeker-Maus, and Yannick Khong from RTINGS assess the Brooks Glycerin 22 as a premium daily trainer that excels in delivering smooth, plush comfort, particularly for heel strikers, thanks to its updated midsole and well-cushioned heel. The shoe’s “DNA Tuned” dual-density cushioning offers solid impact absorption and excellent lateral stability, making it a reliable, stable choice for everyday use and walking. However, the review highlights notable drawbacks: the shoe’s heavy weight and limited energy return result in a sluggish feel and reduced efficiency, especially for racing or long-distance runs. The forefoot cushioning is less protective and tends to bottom out over extended mileage, diminishing comfort during longer efforts. While the Glycerin 22 stands out for its comfort and stability, it falls short in responsiveness and speed, making it better suited for casual training rather than competitive racing or fast-paced workouts.
David Salas, PT, DPT, CSCS from Doctors of Running highlights the Brooks Glycerin 22 as a well-balanced, premium daily training shoe that delivers a plush yet responsive ride thanks to its innovative DNA Tuned midsole. This nitrogen-infused foam uses different cell sizes to provide a softer heel cushioning and a snappier forefoot push-off, making it a notable improvement over previous models. The shoe fits true to size with a secure lockdown and a roomy forefoot, though the heel counter is quite stiff and may not suit everyone. Stability is solid for a neutral trainer, aided by a wide base and good outsole traction, though the softer foam slightly reduces rearfoot stability. Salas appreciates the shoe’s traditional high-drop geometry and moderate flexibility, recommending it for runners seeking a comfortable, reliable daily trainer with a smooth ride. Minor critiques include a desire for a more rounded heel bevel to ease initial contact and a slightly plusher heel counter for added comfort.
David Marquez, David Kroeker-Maus, and Yannick Khong from RTINGS assess the Brooks Glycerin 22 as a premium daily trainer that excels in delivering smooth, plush comfort, particularly for heel strikers, thanks to its updated midsole and well-cushioned heel. The shoe’s “DNA Tuned” dual-density cushioning offers solid impact absorption and excellent lateral stability, making it a reliable, stable choice for everyday use and walking. However, the review highlights notable drawbacks: the shoe’s heavy weight and limited energy return result in a sluggish feel and reduced efficiency, especially for racing or long-distance runs. The forefoot cushioning is less protective and tends to bottom out over extended mileage, diminishing comfort during longer efforts. While the Glycerin 22 stands out for its comfort and stability, it falls short in responsiveness and speed, making it better suited for casual training rather than competitive racing or fast-paced workouts.
David Salas, PT, DPT, CSCS from Doctors of Running highlights the Brooks Glycerin 22 as a well-balanced, premium daily training shoe that delivers a plush yet responsive ride thanks to its innovative DNA Tuned midsole. This nitrogen-infused foam uses different cell sizes to provide a softer heel cushioning and a snappier forefoot push-off, making it a notable improvement over previous models. The shoe fits true to size with a secure lockdown and a roomy forefoot, though the heel counter is quite stiff and may not suit everyone. Stability is solid for a neutral trainer, aided by a wide base and good outsole traction, though the softer foam slightly reduces rearfoot stability. Salas appreciates the shoe’s traditional high-drop geometry and moderate flexibility, recommending it for runners seeking a comfortable, reliable daily trainer with a smooth ride. Minor critiques include a desire for a more rounded heel bevel to ease initial contact and a slightly plusher heel counter for added comfort.
David Marquez, David Kroeker-Maus, and Yannick Khong from RTINGS assess the Brooks Glycerin 22 as a premium daily trainer that excels in delivering smooth, plush comfort, particularly for heel strikers, thanks to its updated midsole and well-cushioned heel. The shoe’s “DNA Tuned” dual-density cushioning offers solid impact absorption and excellent lateral stability, making it a reliable, stable choice for everyday use and walking. However, the review highlights notable drawbacks: the shoe’s heavy weight and limited energy return result in a sluggish feel and reduced efficiency, especially for racing or long-distance runs. The forefoot cushioning is less protective and tends to bottom out over extended mileage, diminishing comfort during longer efforts. While the Glycerin 22 stands out for its comfort and stability, it falls short in responsiveness and speed, making it better suited for casual training rather than competitive racing or fast-paced workouts.
David Salas, PT, DPT, CSCS from Doctors of Running highlights the Brooks Glycerin 22 as a well-balanced, premium daily training shoe that delivers a plush yet responsive ride thanks to its innovative DNA Tuned midsole. This nitrogen-infused foam uses different cell sizes to provide a softer heel cushioning and a snappier forefoot push-off, making it a notable improvement over previous models. The shoe fits true to size with a secure lockdown and a roomy forefoot, though the heel counter is quite stiff and may not suit everyone. Stability is solid for a neutral trainer, aided by a wide base and good outsole traction, though the softer foam slightly reduces rearfoot stability. Salas appreciates the shoe’s traditional high-drop geometry and moderate flexibility, recommending it for runners seeking a comfortable, reliable daily trainer with a smooth ride. Minor critiques include a desire for a more rounded heel bevel to ease initial contact and a slightly plusher heel counter for added comfort.
David Marquez, David Kroeker-Maus, and Yannick Khong from RTINGS assess the Brooks Glycerin 22 as a premium daily trainer that excels in delivering smooth, plush comfort, particularly for heel strikers, thanks to its updated midsole and well-cushioned heel. The shoe’s “DNA Tuned” dual-density cushioning offers solid impact absorption and excellent lateral stability, making it a reliable, stable choice for everyday use and walking. However, the review highlights notable drawbacks: the shoe’s heavy weight and limited energy return result in a sluggish feel and reduced efficiency, especially for racing or long-distance runs. The forefoot cushioning is less protective and tends to bottom out over extended mileage, diminishing comfort during longer efforts. While the Glycerin 22 stands out for its comfort and stability, it falls short in responsiveness and speed, making it better suited for casual training rather than competitive racing or fast-paced workouts.
YouTube
15 LEADING EXPERT & INFLUENCER REVIEWS
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Kofuzi praises the Brooks Glycerin 22 for its stable, comfortable ride and innovative DNA Tuned dual-density midsole, highlighting its plush heel and breathable upper. However, he finds it less soft and a bit clunky compared to the Glycerin Max, making it better suited for heavier runners or those seeking motion control rather than speed.
Alex Cyr from Marathon Handbook praises the Brooks Glycerin 22 as a major leap forward, highlighting its innovative nitrogen-infused DNA Tuned foam with dual-cell technology that delivers plush cushioning and responsive toe-offs. He values its balance of comfort and bounce for easy runs, though notes the taller stack and higher price may not suit everyone.
Social
3 INFLUENCER REVIEWS
Run Shoe Bible highlights the Brooks Glycerin 22’s innovative DNA Tuned nitrogen-infused midsole, praising its dual-density foam for a soft yet responsive ride. They note the shoe’s plush upper and wide base add stability and comfort, though the slight weight increase is a minor drawback. The durable outsole promises longevity. Overall, Run Shoe Bible finds the Glycerin 22 a reliable daily trainer with a subtle performance edge, recommending it for runners seeking comfort and durability with a modern twist, despite the small weight tradeoff.
Road Trail Run highlights the Brooks Glycerin 22’s enhanced stability and secure fit, praising its dialed-in upper and springy DNA Tuned dual-density foam midsole. They note the shoe leans more toward inherent stability without being overbearing, offering a balanced upgrade from previous versions. While specific drawbacks aren’t emphasized, the review conveys thoughtful insight into the shoe’s design improvements and performance feel. Overall, Road Trail Run finds the Glycerin 22 to be a solid, well-rounded trainer ideal for runners seeking comfort and stability. The recommendation is positive but measured, suggesting it’s a dependable choice for those valuing a stable yet responsive ride, with a price point reflecting its premium features.
Run Shoe Bible highlights the Brooks Glycerin 22’s innovative DNA Tuned nitrogen-infused midsole, praising its dual-density foam for a soft yet responsive ride. They note the shoe’s plush upper and wide base add stability and comfort, though the slight weight increase is a minor drawback. The durable outsole promises longevity. Overall, Run Shoe Bible finds the Glycerin 22 a reliable daily trainer with a subtle performance edge, recommending it for runners seeking comfort and durability with a modern twist, despite the small weight tradeoff.
Road Trail Run highlights the Brooks Glycerin 22’s enhanced stability and secure fit, praising its dialed-in upper and springy DNA Tuned dual-density foam midsole. They note the shoe leans more toward inherent stability without being overbearing, offering a balanced upgrade from previous versions. While specific drawbacks aren’t emphasized, the review conveys thoughtful insight into the shoe’s design improvements and performance feel. Overall, Road Trail Run finds the Glycerin 22 to be a solid, well-rounded trainer ideal for runners seeking comfort and stability. The recommendation is positive but measured, suggesting it’s a dependable choice for those valuing a stable yet responsive ride, with a price point reflecting its premium features.
Store Reviews
CUSTOMER REVIEWS FROM 1 STORE
Amazon reviewers consistently praise the Brooks Glycerin 22 for its exceptional comfort and solid arch support, often describing the cushioning as “cloud-like” and ideal for long days on foot. Many highlight the shoe’s ability to keep feet, ankles, and knees comfortable during extended walking or running sessions, with some users noting it helped them avoid soreness after activities like amusement park visits. Customers appreciate the shoe’s high-quality construction and durability, emphasizing that it maintains comfort well up to around 75-100 miles of use. The fit receives positive remarks, especially for accommodating wide feet and custom orthotics, while the secure lacing system earns approval for staying tight during movement. Reviewers also admire the shoe’s understated yet attractive style, which pairs well with casual wear. Although some find the sizing runs small or the extra-wide option narrower than expected, others confirm it fits true to size. Opinions on value vary, with several users considering the price justified by the shoe’s performance and longevity, while a few wish for more color options in wider widths. Overall, Amazon users celebrate the Brooks Glycerin 22 as a comfortable, supportive, and well-made running shoe that excels in cushioning and fit.
4.6 Stars / Many verified reviews
Forum Reviews
CUSTOMER REVIEWS FROM 1 FORUM
Reddit users generally have mixed feelings about the Brooks Glycerin 22, with many appreciating its improved cushioning, comfort, and suitability for long, easy runs, especially compared to previous models. The shoe is praised for its supportive feel and durability, making it a solid choice for those on their feet for extended periods. However, critiques focus on the narrower toe box, firmer midsole, and issues with fit, particularly for wider feet, leading some to prefer earlier versions like the Glycerin 20 or 21. Heavy runners note some concerns about stability and noise, while others find the shoe lighter and more responsive. Overall, longtime users often express disappointment with the design changes, whereas new shoppers tend to find it comfortable but sometimes too firm or narrow.
Many comments
In-Depth Review
Highlights
- •Plush cushioningReviewers report cloud-like impact absorption
- •DNA Tuned dual-cell midsoleMarketed as nitrogen-infused dual-density foam
- •Stable ride and smooth transitionsBroad platform aids heel-to-toe transitions
- •Breathable engineered knit upperFlexible, breathable upper accommodates orthotics
- •Durability for everyday useComfort holds up roughly 75–100 miles
- •Foot‑health certificationsPDAC A5500 and APMA endorsements
Considerations
- •Narrow toe box and fit variabilityMany report snug toe box
- •Heavier-than-average weightHeavier than many daily trainers
- •Forefoot cushioning may bottom outForefoot may bottom out after 75–100 miles
- •Less suited for speedworkLess responsive for fast paces
- •Stiff or bulky heel counterSome report heel stiffness causing discomfort
- •Limited/ tighter extra-wide optionsExtra-wide options sometimes fit tighter
Brooks continues to build on its reputation for reliable, comfortable running shoes with the Glycerin 22—a plush neutral trainer aimed at daily miles and long-haul comfort. Designed especially for heel strikers craving a blend of softness and responsiveness, it introduces the innovative DNA Tuned nitrogen-infused dual-cell foam, delivering cushy landings with a springy toe-off that sets it apart from previous models. The shoe’s broad platform and tuned midsole geometry offer stability without feeling bulky, while its generous 38-39mm stack height paired with a classic 10mm drop caters to runners who prefer extra protection over lightweight speed. A breathable engineered knit upper ensures your feet stay cool, though fit quirks mean sizing up may be wise—especially if you have wider feet. Durability holds strong through roughly 75–100 miles before some cushioning fade kicks in, and yes, this premium trainer carries a bit more heft than rivals aiming for featherlight flair. If comfort and steady support top your checklist, keep reading—you’ll want all the details before lacing up.

Upper Fit and Breathability
The engineered double jacquard knit upper offers more than just looks—it flexes beautifully while keeping feet cool with high breathability that's perfect for sweaty sessions or warm weather outings. Designed true to size but advising half-size up particularly for wide-footers due to occasional snugness, it strikes an impressive balance between secure lockdown and roomy accommodation where it counts most. However, some feedback points out extra-wide options can run tighter than expected; still, overall it's a breathable embrace fans find hard not to love.

Cushioning (DNA Tuned dual-cell foam)
Step into a cloud with the Brooks Glycerin 22’s DNA Tuned dual-cell nitrogen-infused foam, engineered for plush heel cushioning and lively forefoot responsiveness. This clever tech blends larger cells at the heel for soft landings with smaller, denser cells up front to spring you forward, crafting an ideal balance between comfort and propulsion. While some runners find this combo less forgiving after around 75-100 miles, it consistently delivers a luxurious yet energetic ride praised by both experts and users alike as a standout feature.

Stability and Ride Transitions
Brooks nails stability without sacrificing smoothness in the Glycerin 22, thanks to its broad platform and tuned midsole geometry that offer confident foot placement through every stride. The shoe’s modest rocker profile facilitates effortless heel-to-toe transitions, making it especially friendly for heel strikers craving steady support without feeling boxed in. Users appreciate how this blend reduces injury risk while maintaining nimble movement—a rare feat that balances secure footing with just enough bounce to keep runs enjoyable.

Stack Height and Heel-to-Toe Drop
Boasting a generous stack height of about 38-39mm in the heel tapering to roughly 28-29mm upfront, paired with a classic 10mm drop, the Glycerin 22 positions itself firmly among max-cushion trainers catering to those who love their elevation. This setup favors runners seeking shock absorption on long hauls or recovery days but might feel heavy or stiff during speedier efforts. It's no surprise then that reviewers note this geometry supports endurance over quickness—perfectly tailored for those prioritizing comfort over racing edge.

Conclusion
When comfort meets clever engineering, you get a shoe that excels in DNA Tuned dual-cell foam cushioning, delivering plush heel landings and a lively forefoot snap. Its stability and ride transitions feel confident yet fluid—no wobble without the weight of clunky bulk. The generous stack height paired with a classic 10mm drop soothes tired joints but leans away from speed demons craving nimbleness. Breathable jacquard knit uppers hug feet securely, though those with wider toes might find themselves sizing up to dodge snug spots. Durability impresses for daily miles, holding its cushy charm until around 75-100 hits before subtle softening sets in. While it carries some heft compared to featherweights, this extra ounce is the price for steady support on long hauls. For runners who prize plush stability over sprinter agility, this is a smart bet—a thoughtful blend of comfort, responsiveness, and lasting wear that rewards patience with every stride.
Feature Scores
This reflects reviews and ratings from established critics, journalists, and users who have evaluated the item. Their opinions provide a comprehensive assessment.
Performance
Traction
4/5
Cushioning
5/5
Support Stability
4/5
Durability
4/5
Breathability
4/5
Weight
3/5
Responsiveness
4/5
Fit Accuracy
4/5
Value
Price-to-Quality Ratio
4/5
Design
Aesthetic Appeal
4/5
Ergonomic Fit
4/5
Versatility
4/5
Health
Material Safety
4/5
Moisture Management
4/5
Antimicrobial Odor Control
3/5
Safety
Slip Resistance
4/5
Impact Protection
4/5
Ankle Support
2/5
Toe Protection
3/5
Visibility Reflectivity
2/5
Sustainability
Sustainable Materials Use
4/5
Recyclability
3/5
Repairability
2/5
Packaging Waste Reduction
2/5
Experience Style
Adjustability
4/5
Closure Convenience
4/5
Customization Options
3/5
Feature Richness
4/5
Specifications
This section outlines the product's key facts, covering essential features, details, dimensions, materials, and any unique characteristics that define its functionality and usability.
Performance
Value
Design
Safety
Sustainability
Experience Style
Frequently Asked Questions
7 Questions












